Product Name :
LX1606 (Hippurate)
Description:
Telotristat, also known as LP-778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity. Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical- and infection-induced intestinal inflammation.
CAS:
1137608-69-5
Molecular Weight:
754.15
Formula:
C36H35ClF3N7O6
Chemical Name:
2-(phenylformamido)acetic acid; ethyl (2S)-2-amino-3-(4-2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-ylphenyl)propanoate
Smiles :
CC1C=CN(N=1)C1=CC(Cl)=CC=C1[C@@H](OC1=CC(=NC(N)=N1)C1C=CC(C[C@H](N)C(=O)OCC)=CC=1)C(F)(F)F.OC(=O)CNC(=O)C1C=CC=CC=1
InChiKey:
XSFPZBUIBYMVEA-CELUQASASA-N
InChi :
InChI=1S/C27H26ClF3N6O3.C9H9NO3/c1-3-39-25(38)20(32)12-16-4-6-17(7-5-16)21-14-23(35-26(33)34-21)40-24(27(29,30)31)19-9-8-18(28)13-22(19)37-11-10-15(2)36-37;11-8(12)6-10-9(13)7-4-2-1-3-5-7/h4-11,13-14,20,24H,3,12,32H2,1-2H3,(H2,33,34,35);1-5H,6H2,(H,10,13)(H,11,12)/t20-,24+;/m0.Riboflavin Endogenous Metabolite /s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Telotristat, also known as LP-778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity.Ecromeximab Purity & Documentation Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical- and infection-induced intestinal inflammation.|Product information|CAS Number: 1137608-69-5|Molecular Weight: 754.15|Formula: C36H35ClF3N7O6|Chemical Name: 2-(phenylformamido)acetic acid; ethyl (2S)-2-amino-3-(4-2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-ylphenyl)propanoate|Smiles: CC1C=CN(N=1)C1=CC(Cl)=CC=C1[C@@H](OC1=CC(=NC(N)=N1)C1C=CC(C[C@H](N)C(=O)OCC)=CC=1)C(F)(F)F.PMID:32119450 OC(=O)CNC(=O)C1C=CC=CC=1|InChiKey: XSFPZBUIBYMVEA-CELUQASASA-N|InChi: InChI=1S/C27H26ClF3N6O3.C9H9NO3/c1-3-39-25(38)20(32)12-16-4-6-17(7-5-16)21-14-23(35-26(33)34-21)40-24(27(29,30)31)19-9-8-18(28)13-22(19)37-11-10-15(2)36-37;11-8(12)6-10-9(13)7-4-2-1-3-5-7/h4-11,13-14,20,24H,3,12,32H2,1-2H3,(H2,33,34,35);1-5H,6H2,(H,10,13)(H,11,12)/t20-,24+;/m0./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
