Product Name :
Asiatic acid
Description:
Asiatic acid, a pentacyclic triterpene found in Centella asiatica, induces apoptosis in melanoma cells. Asiatic acid has the potential for skin cancer treatment[1]. Asiatic acid also has anti-inflammatory activities.
CAS:
464-92-6
Molecular Weight:
488.70
Formula:
C30H48O5
Chemical Name:
(1S, 2R, 4aS, 6aS, 6bR, 8aR, 9R, 10R, 11R, 12aR, 12bR, 14bS)-10, 11-dihydroxy-9-(hydroxymethyl)-1, 2, 6a, 6b, 9, 12a-hexamethyl-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 12b, 13, 14b-icosahydropicene-4a-carboxylic acid
Smiles :
C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@H]4[C@@]3(C)CC[C@H]3[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]43C)[C@@H]2[C@H]1C)C(O)=O
InChiKey:
JXSVIVRDWWRQRT-UYDOISQJSA-N
InChi :
InChI=1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tauro-β-muricholic acid} site|{Tauro-β-muricholic acid} FXR|{Tauro-β-muricholic acid} Epigenetics|{Tauro-β-muricholic acid} Biological Activity|{Tauro-β-muricholic acid} In Vitro|{Tauro-β-muricholic acid} supplier}
Shelf Life:
≥360 days if stored properly.{{Mosunetuzumab} medchemexpress|{Mosunetuzumab} CD20|{Mosunetuzumab} Purity & Documentation|{Mosunetuzumab} In stock|{Mosunetuzumab} custom synthesis|{Mosunetuzumab} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32715812
Additional information:
Asiatic acid, a pentacyclic triterpene found in Centella asiatica, induces apoptosis in melanoma cells. Asiatic acid has the potential for skin cancer treatment[1]. Asiatic acid also has anti-inflammatory activities.|Product information|CAS Number: 464-92-6|Molecular Weight: 488.70|Formula: C30H48O5|Chemical Name: (1S, 2R, 4aS, 6aS, 6bR, 8aR, 9R, 10R, 11R, 12aR, 12bR, 14bS)-10, 11-dihydroxy-9-(hydroxymethyl)-1, 2, 6a, 6b, 9, 12a-hexamethyl-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 12b, 13, 14b-icosahydropicene-4a-carboxylic acid|Smiles: C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@H]4[C@@]3(C)CC[C@H]3[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]43C)[C@@H]2[C@H]1C)C(O)=O|InChiKey: JXSVIVRDWWRQRT-UYDOISQJSA-N|InChi: InChI=1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 62.5 mg/mL (127.89 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Huang SS, et al. Antinociceptive activities and the mechanisms of anti-inflammation of asiatic Acid in mice. Evid Based Complement Alternat Med. 2011;2011:895857.Park BC, et al. Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells. Cancer Lett. 2005 Jan 31;218(1):81-90.Products are for research use only. Not for human use.|
