Product Name :
Levocetirizine
Description:
Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria.
CAS:
130018-77-8
Molecular Weight:
388.89
Formula:
C21H25ClN2O3
Chemical Name:
2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Smiles :
OC(=O)COCCN1CCN(CC1)[C@H](C1C=CC=CC=1)C1C=CC(Cl)=CC=1
InChiKey:
ZKLPARSLTMPFCP-OAQYLSRUSA-N
InChi :
InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)/t21-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Menin-MLL inhibitor 21} medchemexpress|{Menin-MLL inhibitor 21} JAK|{Menin-MLL inhibitor 21} Purity & Documentation|{Menin-MLL inhibitor 21} In stock|{Menin-MLL inhibitor 21} custom synthesis|{Menin-MLL inhibitor 21} Cancer}
Additional information:
Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria.|Product information|CAS Number: 130018-77-8|Molecular Weight: 388.89|Formula: C21H25ClN2O3|Chemical Name: 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid|Smiles: OC(=O)COCCN1CCN(CC1)[C@H](C1C=CC=CC=1)C1C=CC(Cl)=CC=1|InChiKey: ZKLPARSLTMPFCP-OAQYLSRUSA-N|InChi: InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)/t21-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Etrasimod} medchemexpress|{Etrasimod} LPL Receptor|{Etrasimod} Technical Information|{Etrasimod} In Vivo|{Etrasimod} custom synthesis|{Etrasimod} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:32959705 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Levocetirizine (0.4 mg/kg; oral administration; male Sprague-Dawley rats) treatment shows that the Cmax, AUC0-t , AUC0-∞ and t1/2 are 0.34 μg/mL, 3.26 μg h/mL, 3.67 μg h/mL and 2.34 hours, respectively in Sprague-Dawley rats.|Products are for research use only. Not for human use.|
