Product Name :
Amelubant
Description:
Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM in vital cells and membranes. Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity.
CAS:
346735-24-8
Molecular Weight:
538.63
Formula:
C33H34N2O5
Chemical Name:
ethyl N-(4-{[3-({4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy}methyl)phenyl]methoxy}benzenecarboximidoyl)carbamate
Smiles :
CCOC(=O)NC(=N)C1C=CC(=CC=1)OCC1C=C(COC2C=CC(=CC=2)C(C)(C)C2C=CC(O)=CC=2)C=CC=1
InChiKey:
SBVYURPQULDJTI-UHFFFAOYSA-N
InChi :
InChI=1S/C33H34N2O5/c1-4-38-32(37)35-31(34)25-8-16-29(17-9-25)39-21-23-6-5-7-24(20-23)22-40-30-18-12-27(13-19-30)33(2,3)26-10-14-28(36)15-11-26/h5-20,36H,4,21-22H2,1-3H3,(H2,34,35,37)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM in vital cells and membranes.{{Anacetrapib} medchemexpress|{Anacetrapib} PCSK9|{Anacetrapib} Protocol|{Anacetrapib} In Vitro|{Anacetrapib} custom synthesis|{Anacetrapib} Cancer} Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315.{{Plinabulin} MedChemExpress|{Plinabulin} Microtubule/Tubulin|{Plinabulin} Technical Information|{Plinabulin} In Vivo|{Plinabulin} custom synthesis|{Plinabulin} Epigenetics} Anti-inflammatory activity.PMID:24516446 |Product information|CAS Number: 346735-24-8|Molecular Weight: 538.63|Formula: C33H34N2O5|Chemical Name: ethyl N-(4-{[3-({4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy}methyl)phenyl]methoxy}benzenecarboximidoyl)carbamate|Smiles: CCOC(=O)NC(=N)C1C=CC(=CC=1)OCC1C=C(COC2C=CC(=CC=2)C(C)(C)C2C=CC(O)=CC=2)C=CC=1|InChiKey: SBVYURPQULDJTI-UHFFFAOYSA-N|InChi: InChI=1S/C33H34N2O5/c1-4-38-32(37)35-31(34)25-8-16-29(17-9-25)39-21-23-6-5-7-24(20-23)22-40-30-18-12-27(13-19-30)33(2,3)26-10-14-28(36)15-11-26/h5-20,36H,4,21-22H2,1-3H3,(H2,34,35,37)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Amelubant is a prodrug of active metabolites BIIL 260 and BIIL 315, which are reversible and competitive LTB4 receptor antagonists, with Kis of 1.4, 1.1 nM and 1.7, 1.9 nM in vital cells and membranes, respectively.|Products are for research use only. Not for human use.|
