Product Name :
FNC-TP trisodium
Description:
FNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV.
CAS:
Molecular Weight:
592.11
Formula:
C9H11FN6Na3O13P3
Chemical Name:
sodium ((2R, 3R, 4S, 5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-azido-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate
Smiles :
[N-]=[N+]=N[C@]1(COP(=O)(OP(=O)(OP(O)(=O)O[Na])O[Na])O[Na])O[C@H]([C@@H](F)[C@@H]1O)N1C=CC(N)=NC1=O
InChiKey:
GPPSNTNXFLRJHS-WUCFMPIVSA-K
InChi :
InChI=1S/C9H14FN6O13P3.3Na/c10-5-6(17)9(14-15-12,27-7(5)16-2-1-4(11)13-8(16)18)3-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h1-2,5-7,17H,3H2,(H,22,23)(H,24,25)(H2,11,13,18)(H2,19,20,21);;;/q;3*+1/p-3/t5-,6-,7+,9+;;;/m0…/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Vudalimab} medchemexpress|{Vudalimab} CTLA-4|{Vudalimab} Purity & Documentation|{Vudalimab} Description|{Vudalimab} supplier|{Vudalimab} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
FNC-TP trisodium is the intracellular active form of FNC.{{Deoxycholic acid sodium salt} site|{Deoxycholic acid sodium salt} GPCR/G Protein|{Deoxycholic acid sodium salt} Purity & Documentation|{Deoxycholic acid sodium salt} In Vivo|{Deoxycholic acid sodium salt} supplier|{Deoxycholic acid sodium salt} Autophagy} FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV.|Product information|Molecular Weight: 592.11|Formula: C9H11FN6Na3O13P3|Chemical Name: sodium ((2R, 3R, 4S, 5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-azido-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate|Smiles: [N-]=[N+]=N[C@]1(COP(=O)(OP(=O)(OP(O)(=O)O[Na])O[Na])O[Na])O[C@H]([C@@H](F)[C@@H]1O)N1C=CC(N)=NC1=O|InChiKey: GPPSNTNXFLRJHS-WUCFMPIVSA-K|InChi: InChI=1S/C9H14FN6O13P3.PMID:24513027 3Na/c10-5-6(17)9(14-15-12,27-7(5)16-2-1-4(11)13-8(16)18)3-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h1-2,5-7,17H,3H2,(H,22,23)(H,24,25)(H2,11,13,18)(H2,19,20,21);;;/q;3*+1/p-3/t5-,6-,7+,9+;;;/m0…/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|FNC (0.1-10 nM; 24-240 h) is found mainly to accumulate in these HIV-1 target cells, and the retention of FNC-TP is 2-4 times higher than in other types of cells.|In Vivo:|FNC (1-6 mg/kg; a single p.o.) could enter rhesus macaque PBMCs and form the active nucleoside triphosphate FNC-TP.|Products are for research use only. Not for human use.|
