Product Name :
Efavirenz-d5
Description:
Efavirenz-d5 (DMP 266-d5) is the deuterium labeled Efavirenz. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
CAS:
1132642-95-5
Molecular Weight:
320.71
Formula:
C14H9ClF3NO2
Chemical Name:
(4S)-6-chloro-4-{2-[(1,2,2,3,3-²H₅)cyclopropyl]ethynyl}-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
Smiles :
[2H]C1(C#C[C@@]2(OC(=O)NC3=CC=C(Cl)C=C23)C(F)(F)F)C([2H])([2H])C1([2H])[2H]
InChiKey:
XPOQHMRABVBWPR-XWJABCKYSA-N
InChi :
InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1/i1D2,2D2,8D
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Streptavidin Magnetic Beads} medchemexpress|{Streptavidin Magnetic Beads} Purity & Documentation|{Streptavidin Magnetic Beads} Purity|{Streptavidin Magnetic Beads} supplier|{Streptavidin Magnetic Beads} Autophagy}
Additional information:
Efavirenz-d5 (DMP 266-d5) is the deuterium labeled Efavirenz.{{Losartan} medchemexpress|{Losartan} GPCR/G Protein|{Losartan} Protocol|{Losartan} Data Sheet|{Losartan} custom synthesis|{Losartan} Epigenetics} Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.PMID:24635174 |Product information|CAS Number: 1132642-95-5|Molecular Weight: 320.71|Formula: C14H9ClF3NO2|Chemical Name: (4S)-6-chloro-4-{2-[(1,2,2,3,3-²H₅)cyclopropyl]ethynyl}-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one|Smiles: [2H]C1(C#C[C@@]2(OC(=O)NC3=CC=C(Cl)C=C23)C(F)(F)F)C([2H])([2H])C1([2H])[2H]|InChiKey: XPOQHMRABVBWPR-XWJABCKYSA-N|InChi: InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1/i1D2,2D2,8D|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.|Products are for research use only. Not for human use.|
