SSX2 Antibody Summary
| Immunogen |
SSX2 (AAH02818.1, 1 a.a. – 223 a.a.) full-length human protein. MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTKLGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGNREAQEKEERRGTAHRWSSQNTHNIGRFSLSTSMGAVHGTPKTITHNRDPKGGNMPGPTDCVRENSW
|
| Specificity |
Reacts with synovial sarcoma, X breakpoint 2.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
SSX2
|
| Purity |
Protein A purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Protein A purified
|
Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for SSX2 Antibody
- Cancer/testis antigen 5.2
- cancer/testis antigen family 5, member 2a
- CT5.2a
- HD21
- HOM-MEL-40
- MGC119055
- MGC15364
- MGC3884
- protein SSX2
- sarcoma, synovial, X-chromosome-related 2
- SSX
- SSX2A
- SSX2B
- synovial sarcoma, X breakpoint 2B
- synovial sarcoma, X breakpoint 2CT5.2
- Tumor antigen HOM-MEL-40
Background
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
