Recombinant Human SPANXB1 Protein Summary
| Description |
SPANXB1 (Human) GST-Tagged Recombinant Protein (P01)
Source: Wheat Germ (in vitro) Amino Acid Sequence: MGQQSSVRRLKRSVPCESNEANEANEANKTMPETPTGDSDPQPAPKKMKTSESSTILVVRYRRNVKRTSPEELVNDHARENRINPDQMEEEEFIEITTERPKK |
| Preparation Method |
in vitro wheat germ expression system
|
| Protein/Peptide Type |
Recombinant Protein
|
| Gene |
SPANXB1
|
Applications/Dilutions
| Application Notes |
Western blot, ELISA. This protein has not been tested for any functionality.would be helpful. This product may contain endotoxins and is not suitable for use with live cells.
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human SPANXB1 Protein
- B1
- C
- Cancer/testis antigen 11.2
- cancer/testis antigen family 11, member 2
- CT11.1
- CT11.2
- CT11.2B1
- CT11.3
- CT11.4
- CTp11
- dJ171K16.1
- NAP-X
- Nuclear-associated protein SPAN-Xb
- Nuclear-associated protein SPAN-Xf
- SPANX family member B/F
- SPANX family, member B1
- SPANX
- SPANXA
- SPAN-Xa
- SPANX-A
- SPANXB
- SPAN-Xb
- SPANX-B
- SPANXB2
- SPANX-C
- SPANX-D
- SPANXE SPANX family, member E
- SPAN-Xf
- SPANX-F
- SPANXF1
- sperm protein associated with the nucleus on the X chromosome B/F
- sperm protein associated with the nucleus, X chromosome, family member B1
Background
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq]
