Recombinant Human SDHD Protein Summary
Description |
SDHD (Human) GST-Tagged Recombinant Protein (P01)
Source: Wheat Germ (in vitro) Amino Acid Sequence: MAVLWRLSAVCGALGGRALLLRTPVVRPAHISAFLQDRPIPEWCGVQHIHLSPSHHSGSKAASLHWTSERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGLGQVVTDYVHGDALQKAAKAGLLALSALTFAGLCYFNYHDVGICKAVAMLWKL |
Preparation Method |
in vitro wheat germ expression system
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Protein/Peptide Type |
Recombinant Protein
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Gene |
SDHD
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Applications/Dilutions
Application Notes |
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.
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Packaging, Storage & Formulations
Storage |
Store at -80C. Avoid freeze-thaw cycles.
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Buffer |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human SDHD Protein
- CBT1
- CII-4
- cybS
- PGL
- PGL1
- QPs3
- SDH4
- succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
- Succinate dehydrogenase complex subunit D
- succinate dehydrogenase complex, subunit D, integral membrane protein
- succinate dehydrogenase ubiquinone cytochrome B small subunit
- Succinate-ubiquinone oxidoreductase cytochrome b small subunit
- Succinate-ubiquinone reductase membrane anchor subunit
Background
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma. [provided by RefSeq]