Recombinant Human NKCC1/SLC12A2 Protein Summary
| Description |
NKCC1/SLC12A2 (Human) GST-Tagged Recombinant Protein
Source: Wheat Germ (in vitro) Amino Acid Sequence: YINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDVVVSVEYSKKSDLDTSKPLSEKPITHKVEEEDGKTATQPLLKKESKGPIVPLNVADQKLLE |
| Preparation Method |
in vitro wheat germ expression system
|
| Protein/Peptide Type |
Partial Recombinant Protein
|
| Gene |
SLC12A2
|
Applications/Dilutions
| Application Notes |
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.
|
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human NKCC1/SLC12A2 Protein
- Basolateral Na-K-Cl symporter
- BSC
- BSC2
- Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1
- NKCC1
- NKCC1MGC104233
- SLC12A2
- solute carrier family 12 (sodium/potassium/chloride transporters), member 2
- solute carrier family 12 member 2
Background
By moving chloride into epithelial cells, the Na-K-Cl cotransporter SLC12A2 aids transcellular movement of chloride across both secretory and absorptive epithelia (Payne et al., 1995 [PubMed 7629105]). See also SLC12A1 (MIM 600839) and SLC12A3 (MIM 600968). [supplied by OMIM]
