Product: D-Lys(Z)-Pro-Arg-pNA (diacetate)
Recombinant Human NF2/Merlin Protein Summary
| Description |
NF2/Merlin (Human) GST-Tagged Recombinant Protein
Source: Wheat Germ (in vitro) Amino Acid Sequence: MVVSLRALLLALRQKPHSTGTIHEVTAQLMMSVRLSFWPVAVCSCVAQMASFILIKAPPQPQQSPQPVLSTLLFMYLPGPAR |
| Protein/Peptide Type |
Recombinant Protein
|
| Gene |
NF2
|
Applications/Dilutions
| Application Notes |
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human NF2/Merlin Protein
- ACN
- BANF
- Merlin
- moesin-ezrin-radixin like
- Moesin-ezrin-radixin-like protein
- moesin-ezrin-radizin-like protein
- neurofibromin 2 (bilateral acoustic neuroma)
- neurofibromin 2 (merlin)
- neurofibromin-2
- NF2
- SCH
- Schwannomerlin
- Schwannomin
Background
Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility. Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.
