PMS1 Antibody (2G10) Summary
| Immunogen |
PMS1 (NP_000525, 26 a.a. – 135 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHILSQKPS
|
| Specificity |
PMS1 – PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
PMS1
|
| Purity |
Ascites
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Ascites
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PMS1 Antibody (2G10)
- DKFZp781M0253
- FLJ98259
- HNPCC3
- hPMS1
- human homolog of yeast mutL
- mismatch repair gene PMSL1
- PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
- PMS1 protein homolog 1
- PMSL1DNA mismatch repair protein PMS1
- postmeiotic segregation increased (S. cerevisiae) 1
- rhabdomyosarcoma antigen MU-RMS-40.10B
- rhabdomyosarcoma antigen MU-RMS-40.10E
Background
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
