Product Name :
Calcitriol Derivatives
Description:
Calcitriol Derivatives is a vitamin D3 analog.
CAS:
2070009-24-2
Molecular Weight:
469.70
Formula:
C30H47NO3
Chemical Name:
3-{[(1R, 3Z, 5S)-3-{2-[(1R, 3aS, 4E, 7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-5-hydroxy-4-methylidenecyclohexyl]oxy}propanenitrile
Smiles :
CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@H](C[C@H](O)C/1=C)OCCC#N
InChiKey:
JEXMJWGETRFCMK-MSCDRTKFSA-N
InChi :
InChI=1S/C30H47NO3/c1-21(9-6-15-29(3,4)33)26-13-14-27-23(10-7-16-30(26,27)5)11-12-24-19-25(34-18-8-17-31)20-28(32)22(24)2/h11-12,21,25-28,32-33H,2,6-10,13-16,18-20H2,1,3-5H3/b23-11+,24-12-/t21-,25-,26-,27+,28+,30-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Difluprednate} site|{Difluprednate} Phospholipase|{Difluprednate} Protocol|{Difluprednate} In Vivo|{Difluprednate} supplier|{Difluprednate} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Calcitriol Derivatives is a vitamin D3 analog.|Product information|CAS Number: 2070009-24-2|Molecular Weight: 469.70|Formula: C30H47NO3|Synonym:|1,25-dihydroxy vit D3 (3-propionitrile ether)|3-(((1R,3S,Z)-3-hydroxy-5-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexyl)oxy)propanenitrile|Chemical Name: 3-{[(1R, 3Z, 5S)-3-{2-[(1R, 3aS, 4E, 7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-5-hydroxy-4-methylidenecyclohexyl]oxy}propanenitrile|Smiles: CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@H](C[C@H](O)C/1=C)OCCC#N|InChiKey: JEXMJWGETRFCMK-MSCDRTKFSA-N|InChi: InChI=1S/C30H47NO3/c1-21(9-6-15-29(3,4)33)26-13-14-27-23(10-7-16-30(26,27)5)11-12-24-19-25(34-18-8-17-31)20-28(32)22(24)2/h11-12,21,25-28,32-33H,2,6-10,13-16,18-20H2,1,3-5H3/b23-11+,24-12-/t21-,25-,26-,27+,28+,30-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{PhIP} medchemexpress|{PhIP} Biological Activity|{PhIP} In Vitro|{PhIP} manufacturer|{PhIP} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:23996047 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Barrera D, Noyola-Martínez N, Avila E, Halhali A, Larrea F, Díaz L. Calcitriol inhibits interleukin-10 expression in cultured human trophoblasts under normal and inflammatory conditions. Cytokine. 2012 Mar;57(3):316-21.Lydia A, Asanuma K, Nonaka K, Takagi M, Jeong KH, Kodama F, Asao R, Asanuma E, Prodjosudjadi W, Tomino Y. Effects of 22-oxa-calcitriol on podocyte injury in adriamycin-induced nephrosis. Am J Nephrol. 2012;35(1):58-68.Michalak K, Wicha J. Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione. J Org Chem. 2011 Aug 19;76(16):6906-11.Products are for research use only. Not for human use.|
