Product Name :
N-(m-PEG4)-N’-(PEG2-acid)-Cy5
Description:
N-(m-PEG4)-N’-(PEG2-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2107273-24-3
Molecular Weight:
741.35
Formula:
C41H57ClN2O8
Chemical Name:
2-[5-(1-{2-[2-(2-carboxyethoxy)ethoxy]ethyl}-3,3-dimethyl-2,3-dihydro-1H-indol-2-ylidene)penta-1,3-dien-1-yl]-3,3-dimethyl-1-(2,5,8,11-tetraoxatridecan-13-yl)-3H-indol-1-ium chloride
Smiles :
[Cl-].COCCOCCOCCOCC[N+]1C2=CC=CC=C2C(C)(C)C=1C=CC=CC=C1N(CCOCCOCCC(O)=O)C2=CC=CC=C2C1(C)C
InChiKey:
NAIZLFADVBMGHZ-UHFFFAOYSA-N
InChi :
InChI=1S/C41H56N2O8.ClH/c1-40(2)33-13-9-11-15-35(33)42(20-23-48-28-27-47-22-19-39(44)45)37(40)17-7-6-8-18-38-41(3,4)34-14-10-12-16-36(34)43(38)21-24-49-29-30-51-32-31-50-26-25-46-5;/h6-18H,19-32H2,1-5H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
N-(m-PEG4)-N’-(PEG2-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2107273-24-3|Molecular Weight: 741.35|Formula: C41H57ClN2O8|Chemical Name: 2-[5-(1-{2-[2-(2-carboxyethoxy)ethoxy]ethyl}-3,3-dimethyl-2,3-dihydro-1H-indol-2-ylidene)penta-1,3-dien-1-yl]-3,3-dimethyl-1-(2,5,8,11-tetraoxatridecan-13-yl)-3H-indol-1-ium chloride|Smiles: [Cl-].{{CHAPS} site|{CHAPS} Purity & Documentation|{CHAPS} References|{CHAPS} custom synthesis|{CHAPS} Epigenetic Reader Domain} COCCOCCOCCOCC[N+]1C2=CC=CC=C2C(C)(C)C=1C=CC=CC=C1N(CCOCCOCCC(O)=O)C2=CC=CC=C2C1(C)C|InChiKey: NAIZLFADVBMGHZ-UHFFFAOYSA-N|InChi: InChI=1S/C41H56N2O8.{{Aliskiren hemifumarate} web|{Aliskiren hemifumarate} Autophagy|{Aliskiren hemifumarate} Protocol|{Aliskiren hemifumarate} In Vivo|{Aliskiren hemifumarate} manufacturer|{Aliskiren hemifumarate} Epigenetic Reader Domain} ClH/c1-40(2)33-13-9-11-15-35(33)42(20-23-48-28-27-47-22-19-39(44)45)37(40)17-7-6-8-18-38-41(3,4)34-14-10-12-16-36(34)43(38)21-24-49-29-30-51-32-31-50-26-25-46-5;/h6-18H,19-32H2,1-5H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:25429455 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
