Alanyl tRNA synthetase Overexpression Lysate (Denatured) Summary
| Description |
Pasmid: pCMV-AARS full-length
|
| Gene |
AARS
|
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).
|
Lysate Details for Alanyl tRNA synthetase
| Type |
Overexpression
|
| Protein State |
Denatured
|
Notes
Quality control test: Transient overexpression cell lysate was tested with Anti-AARS antibody by Western Blots.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Alanyl tRNA synthetase Overexpression Lysate (Denatured)
- alanine tRNA ligase 1, cytoplasmic
- Alanine–tRNA ligase
- alanyl-tRNA synthetase
- alanyl-tRNA synthetase, cytoplasmic
- alaRS
- CMT2N
- EC 6.1.1
- EC 6.1.1.7
- Renal carcinoma antigen NY-REN-42
Background
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq]
