Clathrin Heavy Chain 1/CHC17 RNAi Summary
Specificity |
Homo sapiens clathrin, heavy polypeptide (Hc) (CLTC), mRNA
|
Gene |
CLTC
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Applications/Dilutions
Application Notes |
This RNAi causes protein knockdown.
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Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles.
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Clathrin Heavy Chain 1/CHC17 RNAi
- CHC
- CHC17
- Clathrin Heavy Chain 1
- Clathrin heavy chain on chromosome 17
- clathrin, heavy chain (Hc)
- clathrin, heavy chain
- clathrin, heavy polypeptide (Hc)
- clathrin, heavy polypeptide-like 2
- CLH17
- CLH-17
- CLTC
- CLTCL2
- Hc
- KIAA0034
Background
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains (192 kDa) and three light chains (LCa or LCb, 25-29 kDa) and self assembles into a polyhedral cytoskeletal element. Self assembly facilitates clathrins central role in membrane sorting and selective transport within the cell.