AKR1B1 Antibody Summary
| Immunogen |
AKR1B1 (NP_001619.1, 1 a.a. – 316 a.a.) full-length human protein. MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF
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| Specificity |
AKR1B1 – aldo-keto reductase family 1, member B1 (aldose reductase),
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
AKR1B1
|
| Purity |
Protein A purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
Protein A purified
|
Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for AKR1B1 Antibody
- ADR
- Aldehyde reductase
- Aldo-keto reductase family 1 member B1
- aldo-keto reductase family 1, member B1 (aldose reductase)
- ALDR1aldose reductase
- ALR2
- ARaldehyde reductase 1
- EC 1.1.1
- EC 1.1.1.21
- Lii5-2 CTCL tumor antigen
- low Km aldose reductase
- MGC1804
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. [provided by RefSeq]
