PBR Antibody Summary
| Immunogen |
TSPO (AAH01110.1, 1 a.a. – 169 a.a.) full-length human protein. MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFATTLNYCVWRDNHGWHGGRRLPE
|
| Specificity |
TSPO – translocator protein (18kDa),
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
TSPO
|
| Purity |
Protein A purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Protein A purified
|
Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PBR Antibody
- benzodiazepine peripheral binding site
- BZRPDBI
- IBP
- MBRPBS
- mDRC
- Mitochondrial benzodiazepine receptor
- PBRBPBS
- PBRS
- peripheral benzodiazepine receptor
- Peripheral-type benzodiazepine receptor
- pk18
- PKBSbenzodiazapine receptor (peripheral)
- PTBR
- translocator protein (18kDa)
- translocator protein
Background
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
