NFATC2/NFAT1 Antibody (2A4) Summary
| Immunogen |
NFATC2 (NP_036472 812 a.a. – 921 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HYSPTNQQLRCGSHQEFQHIMYCENFAPGTTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNLDQTYLDDELIDTRLSWIQNIL
|
| Localization |
Nuclear
|
| Specificity |
NFATC2 – nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NFATC2
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for NFATC2/NFAT1 Antibody (2A4)
- NFAT pre-existing subunit
- NFAT transcription complex, preexisting component
- NFAT1
- NFAT1nuclear factor of activated T-cells, cytoplasmic 2
- NFATC2
- NF-ATc2
- NFATP
- NF-ATp
- NFATPnuclear factor of activated T-cells, preexisting component
- nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
- preexisting nuclear factor of activated T-cells 2
- T cell transcription factor NFAT1
- T-cell transcription factor NFAT1
Background
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
